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Tylenol Causes Autism?

Excessive Use of Tylenol Causes Autism Says Doctor

Does too much Tylenol cause Autism or lead too it?

There has been much speculation about vaccinations causing autism. Cuba vaccinates a larger percentage of their children with about the same amount of vaccinations as the United States. Yet, the rate of autism is much less. However, in the US acetaminophen is routinely given to ward of fever, but in Cube no acetaminophen is given. Could there be a link here? Does Tylenol cause autism?

image for tylenol causes autism?Dr. William Shaw of Great Plains Laboratories has studied the relationship and given his report. Ventography, reports the findings in laymens terms with a controversial post. Read the results below.

Is there a link between the use of Tylenol and Autism?

“It appears that the marked increase in the rate of autism throughout much of the world may be largely mediated by the marked increase in the use of acetaminophen in genetically and/or metabolically susceptible children and perhaps the use of acetaminophen by pregnant women.”

Because many children with autism have defective sulfation, they cannot properly detoxify acetaminophen. Therefore, it becomes toxic.

This then leads to intestinal Clostridia bacteria overgrowth.

Then the Clostridia bacteria cause overproduction of brain dopamine and reduced concentrations of brain norepinephrine.

Too much dopamine leads to obsessive, compulsive, and stereotypical behaviors.

Too little norepinephrine leads to reduced exploratory behavior and learning in new environments.

Because sulfation is often defective for people with autism, the body cannot use proper pathways to get rid of acetaminophen. Therefore, the body sends a larger than normal amount of acetaminophen to be detoxified by a pathway called cytochrome p450 2E1.

The problem with this pathway is that it leads to excessive production of N-acetyl-p-benzoquinone imine (NAPQI), a very toxic metabolite.

NAPQI is dangerous because it depletes glutathione which then reduces the body’s ability to detoxify a host of toxic chemicals in the environment.

In addition, the increase of NAPQI creates oxidative stress which leads to protein, lipid, and nucleic acid damage from free radicals. It also causes an increased rate of damage to mitochondrial and nuclear DNA.

NAPQI production has been found to be increased in humans at recommended dosages of acetaminophen and would be expected to be even higher in people with diminished sulfation capacity (as is often seen in autism).

BOTTOM LINE: Question your acetaminophen use.

You can read their full post here. http://ventography.wordpress.com/2012/03/02/update-from-dr-shaw-acetaminophen-and-autism-connection/

Please leave a comment below and tell us your thoughts on this controversial finding. One thing you may be interested in is the fact that excessive tylenol use has been linked to asthma. As reported on NPR, by Patti Neighmond.

Parents and doctors around the world have been alarmed by the dramatic increase in childhood asthma.

One factor in the upswing is better detection by doctors, but at least one doctor thinks a common over-the-counter drug also has something to do with it.

Dr. John McBride sees lots of kids with asthma. He’s a pediatric pulmonologist at Akron Children’s Hospital in Ohio. He knew of studies that raised concern about the safety of acetaminophen — brand name Tylenol — to treat colds and fever in kids with asthma. So he decided to look more closely at the research.

“I was stunned,” he says. All the studies he looked at showed a link between asthma and acetaminophen.

“The more acetaminophen somebody takes, the more likely it is that they have asthma,” he says. “Also, there’s an incredible consistency. Everybody around the world who’s looked for this association has been able to find it.”

Read more here. http://www.npr.org/blogs/health/2012/02/20/147002356/does-tylenol-worsen-asthma-for-kids

There is a lot going on here, we believe this information warrants a deeper investigation.

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